Methamphetamine Abuse Linked To Underage Sex, Smoking And Drinking
Children and adolescents who abuse alcohol or are sexually active are more likely to take methamphetamines (MA), also known as ‘meth’ or ‘speed’. Research published in the open access journal BMC Pediatrics reveals the risk factors associated with MA use, in both low-risk children (those who don’t take drugs) and high-risk children (those who have [...]
Smoking Cessation – Evotec Reports Phase I Safety Data From Tyramine Interaction Study With EVT 302
Evotec AG (Frankfurt Stock Exchange: EVT; NASDAQ: EVTC) announced today encouraging results of a Phase I safety study investigating the potential interaction of EVT 302, a reversible and highly selective inhibitor of monoamine oxidase B (MAO-B) in development for smoking cessation, with tyramine. The study was undertaken to determine potential safety advantages of EVT 302 [...]
Department Of Health Research Shows Women Are Unaware Of Link Between Alcohol And Breast Cancer Risk
New research from the Department of Health’s Know Your Limits campaign reveals that the vast majority of UK women (82%) don’t realise alcohol consumption can increase the risk of developing breast cancer. According to the General Household Survey, around 4 million women drink more than the NHS recommended daily limit of 2-3 units of alcohol, [...]
Educating Chief Residents About Addiction At Boston Medical Center
Researchers from Boston Medical Center (BMC) have found that education on addiction is inadequate during medical training, resulting in suboptimal medical care for those at risk. However, the research also found that a Chief Resident Immersion Training (CRIT) program in addiction medicine is an effective “train the trainers” model for dissemination of addiction knowledge and [...]
Alcohol: A Life Sentence
Every year, almost 4000 babies in Germany are born with alcohol-related defects. The mothers of these children have often drunk alcohol regularly during the pregnancy. The consequences are often devastating and commonly persist into adulthood. The various forms of fetal alcohol spectrum disorders are presented by the pediatricians Hans-Ludwig Spohr and Hans-Christoph Steinhausen in the [...]
Assessment of GABAA Benzodiazepine Receptor (GBzR) Sensitivity in Patients with Alcohol Dependence
Aim: The aim of this study was to measure GABAA benzodiazepine receptor (GBzR) sensitivity in alcohol-dependent patients and compare with matched non-dependent drinkers. Methods: Nine abstinent alcohol-dependent male patients, age matched with nine male non-dependent social drinkers, received an intravenous infusion of midazolam. Objective (saccadic eye movement slowing) and subjective (visual analogue scales) measurements were [...]
Effects of Clozapine on Ethanol Withdrawal Syndrome in Rats
Aims: Co-morbid substance use in schizophrenic patients is common, and an important factor affects the outcome of disease. On the other hand, drug dependence is a predictive factor for psychosis. Alcohol is one of the most frequently abused psychoactive substances and may contribute psychotic symptoms in several conditions, such as withdrawal syndrome. The present study [...]
D-Cycloserine Facilitates Extinction of Conditioned Alcohol-Seeking Behaviour in Rats
Aims: The aim of the present study was to examine the influence of partial NMDA receptor agonist d-cycloserine (DCS) on the extinction of conditioned alcohol-seeking behaviour. Methods: For this purpose, rats were administered with DCS 60 min before each successive extinction session. Resumption of alcohol responding was carried out 1 day after the final extinction [...]